Description

8-Bromo-6-Methyl-1,2,3,4-Tetrahydroquinoline is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. Its core quinoline scaffold, functionalized with bromine and methyl groups, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its halogenated quinoline structure.
• Ligand and Catalyst Synthesis: Employed in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions.
• Material Science: Acts as a building block for organic electronic materials, such as charge-transport layers and light-emitting compounds.
• Chemical Biology: Utilized as a probe or tag in biochemical research due to its modifiable bromine handle.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new synthetic pathways in heterocyclic chemistry.

Basic Information

Product Name	8-Bromo-6-Methyl-1,2,3,4-Tetrahydroquinoline
CAS No.	887749-24-8
Molecular Formula	C10H12BrN
Molecular Weight	226.11 g/mol
Synonyms	6-Methyl-8-bromo-1,2,3,4-tetrahydroquinoline; 8-Bromo-6-methyl-1,2,3,4-tetrahydroquinoline; 1,2,3,4-Tetrahydro-8-bromo-6-methylquinoline; 8-Bromo-6-methyl-3,4-dihydro-2H-quinoline; Tetrahydroquinoline, 8-bromo-6-methyl-; 8-Bromo-6-methyl-1,2,3,4-tetrahydro-quinoline
EINECS	Contact for details

Quality Control

Our 8-Bromo-6-Methyl-1,2,3,4-Tetrahydroquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the high standards required for research and commercial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.