Description

1-(4-Nitro-Phenyl)-Azetidine-3-Carboxylic Acid is a high-value, nitrogen-containing heterocyclic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both an azetidine ring and a nitro-substituted aromatic system, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Chemical Biology & Proteomics: Serves as a valuable scaffold or linker in the design of chemical probes, enzyme inhibitors, and activity-based protein profiling (ABPP) reagents.
• Material Science: Investigated as a monomer or additive for creating specialized polymers with unique thermal or mechanical properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development in organic chemistry and medicinal chemistry programs.
• Custom Synthesis: A starting point for the tailored synthesis of more complex, functionalized azetidine derivatives for specific client projects.

Basic Information

Product Name	1-(4-Nitro-Phenyl)-Azetidine-3-Carboxylic Acid
CAS No.	887595-98-4
Molecular Formula	C10H10N2O4
Molecular Weight	222.20 g/mol
Synonyms	4-Nitro-1-(azetidin-3-yl)benzoic acid; 3-Carboxy-1-(4-nitrophenyl)azetidine; 1-(4-Nitrophenyl)azetidine-3-carboxylic acid; Azetidine-3-carboxylic acid, 1-(4-nitrophenyl)-; 887595-98-4; 1-(p-Nitrophenyl)azetidine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(4-Nitro-Phenyl)-Azetidine-3-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity determination and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, identity, and relevant physical data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.