Description

Quinazoline, 4-Chloro-6,7-Difluoro-2-(Trifluoromethyl)- is a high-value, multi-halogenated quinazoline derivative, identified by CAS NO 887592-35-0, serving as a critical advanced pharmaceutical intermediate. Its complex halogenated structure makes it a key building block for synthesizing novel, potent bioactive molecules, particularly in targeted drug discovery. This compound is essential for R&D and production teams in the pharmaceutical and agrochemical industries seeking to develop next-generation therapeutics and crop protection agents.

Application

This specialized quinazoline derivative is primarily utilized as a sophisticated synthetic precursor in advanced chemical synthesis. Its applications include:

• Pharmaceutical Intermediate: A crucial building block for the synthesis of kinase inhibitors and other targeted small-molecule drugs.
• Agrochemical Research: Used in developing novel active ingredients for herbicides and fungicides.
• Chemical Biology & Proteomics: Serves as a scaffold for creating chemical probes to study enzyme function and disease pathways.
• Material Science: Potential precursor for specialty chemicals and advanced organic electronic materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development.

Basic Information

Product Name	Quinazoline, 4-Chloro-6,7-Difluoro-2-(Trifluoromethyl)-
CAS No.	887592-35-0
Molecular Formula	C10H3ClF5N2
Molecular Weight	281.59 g/mol
Synonyms	4-Chloro-6,7-difluoro-2-(trifluoromethyl)quinazoline; 2-(Trifluoromethyl)-4-chloro-6,7-difluoroquinazoline; 4-Chloro-6,7-difluoro-2-trifluoromethylquinazoline; Quinazoline, 4-chloro-6,7-difluoro-2-(trifluoromethyl)-; 887592-35-0; 4-Chloro-6,7-difluoro-2-(trifluoromethyl)quinazoline
EINECS	Contact for details

Quality Control

Our Quinazoline, 4-Chloro-6,7-Difluoro-2-(Trifluoromethyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.