Description

Quinazoline, 7-Bromo-4-Chloro-2-(1,1-Dimethylethyl)- is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique halogenated and tert-butyl substituted quinazoline core makes it a critical intermediate for researchers developing novel bioactive molecules. This compound is primarily targeted at pharmaceutical R&D and agrochemical laboratories seeking to create new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors, anticancer agents, and other small molecule therapeutics.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and pesticides with enhanced activity.
• Chemical Biology Probe: Serves as a core scaffold for creating tool compounds to study biological pathways and protein function.
• Material Science Precursor: Potential intermediate for synthesizing organic electronic materials and advanced polymers.
• Academic & Contract Research: Enables medicinal chemistry programs in universities and CROs for hit-to-lead optimization.

Basic Information

Product Name	Quinazoline, 7-Bromo-4-Chloro-2-(1,1-Dimethylethyl)-
CAS No.	887592-23-6
Molecular Formula	C₁₃H₁₄BrClN₂
Molecular Weight	313.62 g/mol
Synonyms	7-Bromo-4-chloro-2-tert-butylquinazoline; 2-tert-Butyl-7-bromo-4-chloroquinazoline; 4-Chloro-7-bromo-2-(tert-butyl)quinazoline; 7-Bromo-4-chloro-2-(tert-butyl)quinazoline; 2-(1,1-Dimethylethyl)-7-bromo-4-chloroquinazoline; 7-Bromo-4-chloro-2-(1,1-dimethylethyl)quinazoline; Quinazoline, 7-bromo-4-chloro-2-(1,1-dimethylethyl)-; 887592-23-6
EINECS	Contact for details

Quality Control

Our Quinazoline, 7-Bromo-4-Chloro-2-(1,1-Dimethylethyl)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and full analytical data is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.