Description

6-Methoxy-3,4-Dihydro-2H-Quinoxaline-1-Carboxylic Acid tert-Butyl Ester is a high-value, protected heterocyclic building block essential for advanced organic synthesis. This compound matters as a key intermediate in the development of complex pharmaceutical molecules, particularly those targeting central nervous system and oncological pathways. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel quinoxaline-based scaffolds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those with quinoxaline or dihydroquinoxaline core structures.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for developing new therapeutic agents.
• Process Chemistry Development: Serves as a key starting material (KSM) or advanced intermediate in scaling up synthetic routes for Active Pharmaceutical Ingredients (APIs).
• Agrochemical Synthesis: Employed in the research and development of new pesticides and herbicides that utilize functionalized quinoxaline motifs.
• Fine Chemical Production: Utilized for the custom synthesis of complex, high-value specialty chemicals for various industrial applications.
• Academic & Institutional Research: A valuable reagent for exploring new organic reactions and methodologies in university and institutional laboratories.

Basic Information

Product Name	6-Methoxy-3,4-Dihydro-2H-Quinoxaline-1-Carboxylic Acid tert-Butyl Ester
CAS No.	887590-30-9
Molecular Formula	C14H18N2O3
Molecular Weight	262.31 g/mol
Synonyms	tert-Butyl 6-methoxy-3,4-dihydro-2H-quinoxaline-1-carboxylate; 1-Boc-6-methoxy-1,2,3,4-tetrahydroquinoxaline; 6-Methoxy-1,2,3,4-tetrahydroquinoxaline-1-carboxylic acid tert-butyl ester; 1-N-Boc-6-methoxy-1,2,3,4-tetrahydroquinoxaline; 6-Methoxy-3,4-dihydro-1H-quinoxaline-2-carboxylic acid tert-butyl ester (tautomer); 6-Methoxy-1,2,3,4-tetrahydroquinoxaline-1-N-carboxylic acid tert-butyl ester; Boc-6-methoxy-THQ; 887590-30-9
EINECS	Contact for details

Quality Control

Our 6-Methoxy-3,4-Dihydro-2H-Quinoxaline-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. We provide material that meets high-purity standards suitable for research and development use. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch upon request, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.