Description

3-(3-Bromo-Benzenesulfonyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). Its core value lies in its role as a critical building block, enabling the precise construction of piperidine-based molecular scaffolds essential for modern drug discovery. This compound is primarily needed by research institutions and pharmaceutical manufacturers engaged in developing new therapeutic agents, particularly in areas requiring sulfonamide and halogenated aromatic functionalities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Protease Inhibitor Research: Used in the development of protease inhibitors, where the benzenesulfonyl-piperidine moiety acts as a crucial pharmacophore.
• Chemical Biology & Medicinal Chemistry: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in high-throughput screening.
• API Process Development: Employed in route scouting and optimization for the commercial-scale production of complex APIs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	3-(3-Bromo-Benzenesulfonyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	887590-11-6
Molecular Formula	C16H22BrNO4S
Molecular Weight	404.32 g/mol
Synonyms	1-Boc-3-(3-bromophenylsulfonyl)piperidine; tert-Butyl 3-[(3-bromophenyl)sulfonyl]piperidine-1-carboxylate; 3-(3-Bromobenzenesulfonyl)piperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-3-(3-bromobenzenesulfonyl)piperidine; 3-(3-Bromo-benzenesulfonyl)-piperidine-1-carboxylic acid tert-butyl ester; N-Boc-3-(3-bromophenylsulfonyl)piperidine; 887590-11-6
EINECS	Contact for details

Quality Control

Our 3-(3-Bromo-Benzenesulfonyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and pre-clinical development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.