Description

3-(2-Bromo-Benzenesulfonyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its sulfonyl piperidine scaffold. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for constructing complex molecules with targeted biological activity. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or oncology.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical entities.
• Process Chemistry Development: Serves as a critical starting material or intermediate in the scale-up and optimization of synthetic routes for Active Pharmaceutical Ingredients (APIs).
• Library Synthesis: Employed in combinatorial chemistry and parallel synthesis to generate diverse compound libraries for high-throughput screening.
• Chemical Biology Probes: Can be utilized to develop molecular probes for studying enzyme function or protein-protein interactions.
• Custom Synthesis: A foundational component for contract research and manufacturing organizations (CROs/CMOs) offering bespoke chemical synthesis services.

Basic Information

Product Name	3-(2-Bromo-Benzenesulfonyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	887590-07-0
Molecular Formula	C16H22BrNO4S
Molecular Weight	404.32 g/mol
Synonyms	1-Boc-3-[(2-bromophenyl)sulfonyl]piperidine; tert-Butyl 3-[(2-bromophenyl)sulfonyl]piperidine-1-carboxylate; 3-(2-Bromobenzenesulfonyl)piperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-3-[(2-bromophenyl)sulfonyl]piperidine; N-Boc-3-(2-bromobenzenesulfonyl)piperidine; Piperidine-1-carboxylic acid, 3-[(2-bromophenyl)sulfonyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 3-(2-Bromo-Benzenesulfonyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive pharmaceutical R&D. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of the pharmaceutical industry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.