Description

6-Bromo-4-Chloro-Quinoline-2-Carboxylic Acid Methyl Ester is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in providing a versatile quinoline scaffold with reactive halogen and ester functionalities, enabling precise molecular construction. This compound is critically needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other therapeutic agents.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Used in the research and development of advanced organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Synthesis: Acts as a versatile substrate for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and further functionalization due to its bromo and chloro substituents.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and the exploration of new chemical spaces.

Basic Information

Product Name	6-Bromo-4-Chloro-Quinoline-2-Carboxylic Acid Methyl Ester
CAS No.	887587-50-0
Molecular Formula	C12H7BrClNO2
Molecular Weight	316.55 g/mol
Synonyms	Methyl 6-Bromo-4-Chloroquinoline-2-carboxylate; 6-Bromo-4-Chloro-2-Quinolinecarboxylic Acid Methyl Ester; 2-Quinolinecarboxylic acid, 6-bromo-4-chloro-, methyl ester; 887587-50-0; Methyl 6-bromo-4-chloro-2-quinolinecarboxylate; 4-Chloro-6-bromoquinoline-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 6-Bromo-4-Chloro-Quinoline-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/LC-MS for identity confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.