Description

2-(3-Amino-Propyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, protected amine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs). This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce piperidine and amino-propyl functionalities into target structures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Peptidomimetic Chemistry: Used to incorporate constrained, nitrogen-containing heterocycles into peptide backbones to enhance stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Agrochemical Synthesis: Employed in the research and development of new herbicides, fungicides, and insecticides.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up production under cGMP conditions.
• Academic & Industrial R&D: Used in discovery chemistry for library synthesis and exploring new chemical spaces in medicinal chemistry programs.

Basic Information

Product Name	2-(3-Amino-Propyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	887587-47-5
Molecular Formula	C13H26N2O2
Molecular Weight	242.36 g/mol
Synonyms	1-Boc-2-(3-aminopropyl)piperidine; tert-Butyl 2-(3-aminopropyl)piperidine-1-carboxylate; 2-(3-Aminopropyl)piperidine-1-carboxylic acid tert-butyl ester; 1-N-Boc-2-(3-aminopropyl)piperidine; N-Boc-2-(3-aminopropyl)piperidine; Piperidine-1-carboxylic acid, 2-(3-aminopropyl)-, 1,1-dimethylethyl ester; 887587-47-5
EINECS	Contact for details

Quality Control

Our 2-(3-Amino-Propyl)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up. We provide comprehensive analytical data including HPLC purity, NMR, and MS for identity confirmation. Certificates of Analysis (COA) documenting all release specifications are available for every batch. Our quality system supports development under ICH guidelines and can be tailored for cGMP production upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.