Description

1-Boc-3-([2-(3-Bromo-Phenyl)-Ethylamino]-Methyl)-Piperidine is a high-purity, advanced pharmaceutical intermediate featuring a piperidine scaffold with a bromo-phenyl and Boc-protected amine functionality. This compound is critical for medicinal chemistry research and development, enabling the synthesis of complex molecules with targeted biological activity. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for the creation of novel drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Peptidomimetic Synthesis: Serves as a constrained scaffold in the design of peptide mimics and protease inhibitors.
• Ligand Development: Employed in the creation of selective ligands for G-protein coupled receptors (GPCRs) and other biological targets.
• Chemical Biology Probes: Utilized to develop tool compounds for studying enzyme function and cellular pathways.
• Process Chemistry: Integrated into scalable synthetic routes during the development and optimization of manufacturing processes for APIs.

Basic Information

Product Name	1-Boc-3-([2-(3-Bromo-Phenyl)-Ethylamino]-Methyl)-Piperidine
CAS No.	887587-30-6
Molecular Formula	C20H31BrN2O2
Molecular Weight	411.38 g/mol
Synonyms	1-Boc-3-[(2-(3-Bromophenyl)ethylamino)methyl]piperidine; tert-Butyl 3-({[2-(3-bromophenyl)ethyl]amino}methyl)piperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-3-({[2-(3-bromophenyl)ethyl]amino}methyl)piperidine; 1-Boc-3-({2-[3-Bromophenyl]ethylamino}methyl)piperidine; Piperidine, 3-[[[2-(3-bromophenyl)ethyl]amino]methyl]-, 1-(1,1-dimethylethyl) ester; 887587-30-6
EINECS	Contact for details

Quality Control

Our 1-Boc-3-([2-(3-Bromo-Phenyl)-Ethylamino]-Methyl)-Piperidine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for research-grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.