Description

1-Boc-3-([2-(2-Bromo-Phenyl)-Ethylamino]-Methyl)-Piperidine is a high-purity, advanced pharmaceutical intermediate featuring a piperidine scaffold with a brominated aromatic side chain and a Boc-protected amine. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in the areas of central nervous system (CNS) and oncology drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) for clinical research.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• CNS Drug Development: Serves as a building block for potential neuroactive compounds targeting receptors and enzymes in the brain.
• Oncological Agent Synthesis: Employed in the construction of candidate molecules designed for targeted cancer therapies.
• Chemical Biology Probes: Utilized in the development of tool compounds for investigating biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds under cGMP or research-grade conditions.

Basic Information

Product Name	1-Boc-3-([2-(2-Bromo-Phenyl)-Ethylamino]-Methyl)-Piperidine
CAS No.	887587-26-0
Molecular Formula	C20H31BrN2O2
Molecular Weight	411.38 g/mol
Synonyms	1-Boc-3-[(2-(2-Bromophenyl)ethylamino)methyl]piperidine; tert-Butyl 3-({[2-(2-bromophenyl)ethyl]amino}methyl)piperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-3-({[2-(2-bromophenyl)ethyl]amino}methyl)piperidine; N-{[(1-Boc-3-piperidinyl)methyl]amino}ethyl-2-bromobenzene; 1-Boc-3-(2-(2-bromophenyl)ethylaminomethyl)piperidine; Piperidine, 3-[[[2-(2-bromophenyl)ethyl]amino]methyl]-, 1-(1,1-dimethylethyl) 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 1-Boc-3-([2-(2-Bromo-Phenyl)-Ethylamino]-Methyl)-Piperidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our standard grade meets research and development requirements, and we can support projects requiring cGMP standards for advanced clinical phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.