Description

6-Bromo-2,3-Difluorobenzene Acetic Acid is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound matters as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogenated and fluorinated structure enables precise molecular modifications. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides, leveraging the fluorine atoms for enhanced bioactivity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the production of fluorinated liquid crystals for advanced display technologies.
• Organic Electronic Materials: Employed in the synthesis of fluorinated organic semiconductors and charge-transport materials for OLEDs and OFETs.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D focused on fluorochemistry and heterocyclic compound synthesis.

Basic Information

Product Name	6-Bromo-2,3-Difluorobenzene Acetic Acid
CAS No.	887585-27-5
Molecular Formula	C8H5BrF2O2
Molecular Weight	251.03 g/mol
Synonyms	2-(6-Bromo-2,3-difluorophenyl)acetic acid; 6-Bromo-2,3-difluorophenylacetic acid; Acetic acid, 2-(6-bromo-2,3-difluorophenyl)-; (6-Bromo-2,3-difluorophenyl)acetic acid; 887585-27-5; 6-Br-2,3-diF-PhAA; BDFPAA
EINECS	Contact for details

Quality Control

Our 6-Bromo-2,3-Difluorobenzene Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the stringent requirements for pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (GC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.