Description

3-Amino-3-(2,3-Dichloro-6-Fluoro-Phenyl)-Propionic Acid is a high-purity, non-natural amino acid derivative that serves as a critical building block in advanced organic synthesis. Its unique halogenated phenylalanine-like structure makes it an indispensable intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in protease inhibitor and receptor antagonist research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging its halogenated aromatic ring for enhanced bioactivity and environmental stability.
• Peptidomimetics Research: Serves as a constrained, non-proteinogenic amino acid analog for designing peptide-like molecules with improved metabolic stability and binding affinity.
• Ligand and Catalyst Development: Employed in the preparation of specialized chelating ligands and organocatalysts for asymmetric synthesis.
• Material Science Precursor: Potential monomer for creating specialty polymers with unique functional properties.

Basic Information

Product Name	3-Amino-3-(2,3-Dichloro-6-Fluoro-Phenyl)-Propionic Acid
CAS No.	887583-92-8
Molecular Formula	C9H8Cl2FNO2
Molecular Weight	268.07 g/mol
Synonyms	3-Amino-3-(2,3-dichloro-6-fluorophenyl)propanoic acid; 2,3-Dichloro-6-fluoro-β-phenyl-β-alanine; (R/S)-3-Amino-3-(2,3-dichloro-6-fluorophenyl)propionic acid; β-Amino-(2,3-dichloro-6-fluorophenyl)propionic acid; DL-3-Amino-3-(2,3-dichloro-6-fluoro-phenyl)propionic acid; 3-(2,3-Dichloro-6-fluorophenyl)-3-aminopropanoic acid; Amino-dichloro-fluorophenyl propionic acid
EINECS	Contact for details

Quality Control

Our 3-Amino-3-(2,3-Dichloro-6-Fluoro-Phenyl)-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP intermediate applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent batch-to-batch quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.