Description

5,6,7,8-Tetrahydro-1H-Pyrazolo[3,4-B]Quinolin-3-Ylamine is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrazoloquinoline chemical class. This compound is of significant commercial interest for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the creation of novel chemical libraries for high-throughput screening.
• API Development: Used in the research and development of potential new Active Pharmaceutical Ingredients (APIs), especially in oncology and CNS disorders.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and cGMP production of clinical trial materials.
• Biochemical Research: Employed as a tool compound in biochemical assays to study enzyme inhibition or receptor binding mechanisms.

Basic Information

Product Name	5,6,7,8-Tetrahydro-1H-Pyrazolo[3,4-B]Quinolin-3-Ylamine
CAS No.	887571-91-7
Molecular Formula	C10H12N4
Molecular Weight	188.23 g/mol
Synonyms	3-Amino-5,6,7,8-tetrahydro-1H-pyrazolo[3,4-b]quinoline; 1H-Pyrazolo[3,4-b]quinolin-3-amine, 5,6,7,8-tetrahydro-; 5,6,7,8-Tetrahydro-1H-pyrazolo[3,4-b]quinolin-3-amine; Pyrazolo[3,4-b]quinolin-3-amine, 5,6,7,8-tetrahydro-1H-; Tetrahydro-pyrazoloquinolin-3-ylamine; 887571-91-7; Amine derivative of tetrahydro-pyrazoloquinoline
EINECS	Contact for details

Quality Control

Our 5,6,7,8-Tetrahydro-1H-Pyrazolo[3,4-B]Quinolin-3-Ylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed batch-specific results are provided to guarantee traceability, consistency, and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.