Description

5-(2-Chlorophenyl)-Isoxazole-4-Carboxylic Acid is a high-purity, versatile heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its unique molecular scaffold, which is integral to the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecules with targeted biological activities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Research: Serves as a core structure for developing new herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Chemical Synthesis Building Block: Used in medicinal chemistry and process R&D for constructing complex isoxazole-containing molecules through reactions like amidation, esterification, and cross-coupling.
• Academic & Industrial R&D: Employed in research laboratories for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Material Science Precursor: Potential use in the synthesis of specialty polymers, ligands for catalysis, or organic electronic materials.

Basic Information

Product Name	5-(2-Chlorophenyl)-Isoxazole-4-Carboxylic Acid
CAS No.	887408-06-2
Molecular Formula	C10H6ClNO3
Molecular Weight	223.61 g/mol
Synonyms	5-(2-Chlorophenyl)-1,2-oxazole-4-carboxylic acid; 4-Isoxazolecarboxylic acid, 5-(2-chlorophenyl)-; 5-(o-Chlorophenyl)isoxazole-4-carboxylic Acid; 2-Chloro-5-(4-carboxyisoxazol-5-yl)benzene; 887408-06-2; AI3-52010; SCHEMBL2180771; ZINC000004079753
EINECS	Contact for details

Quality Control

Every batch of 5-(2-Chlorophenyl)-Isoxazole-4-Carboxylic Acid is manufactured and tested under a strict quality management system. We ensure compliance with high-purity standards suitable for research and commercial synthesis. Comprehensive analytical testing, including HPLC, NMR, and LC-MS, is performed to verify identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.