Description

n-Cyclopropyl-2-Nitro-4-(Trifluoromethyl)Aniline is a specialized aromatic amine derivative featuring a nitro group and a trifluoromethyl substituent. This compound is a crucial advanced pharmaceutical intermediate (API) and a versatile building block in synthetic organic chemistry. It is primarily utilized by pharmaceutical R&D and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Serves as a critical building block for developing new herbicides and pesticides, leveraging the biological activity of the aniline and trifluoromethyl motifs.
• Organic Synthesis Building Block: Used in cross-coupling reactions (e.g., Buchwald-Hartwig amination) and functional group transformations to create complex molecular architectures.
• Material Science Research: Investigated as a monomer or functional component in the development of specialty polymers and advanced organic materials.
• Dye & Pigment Intermediate: Acts as a starting material for synthesizing novel azo dyes and pigments due to its aromatic amine structure.

Basic Information

Product Name	n-Cyclopropyl-2-Nitro-4-(Trifluoromethyl)Aniline
CAS No.	887351-41-9
Molecular Formula	C10H9F3N2O2
Molecular Weight	246.19 g/mol
Synonyms	2-Nitro-4-(trifluoromethyl)-N-cyclopropylaniline; 4-(Trifluoromethyl)-2-nitro-N-cyclopropylaniline; N-Cyclopropyl-2-nitro-4-(trifluoromethyl)benzenamine; Benzenamine, N-cyclopropyl-2-nitro-4-(trifluoromethyl)-; 1-Cyclopropylamino-2-nitro-4-trifluoromethylbenzene; 2-Nitro-α,α,α-trifluoro-N-cyclopropyl-p-toluidine
EINECS	Contact for details

Quality Control

Our n-Cyclopropyl-2-Nitro-4-(Trifluoromethyl)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.