Description

Methyl 4-Chloro-6-Trifluoromethyl-Quinoline-2-Carboxylate is a high-purity, multi-functional heterocyclic building block of significant commercial and research interest. Its core value lies in its versatile chemical structure, which serves as a critical intermediate in the synthesis of advanced active ingredients. This compound is primarily needed by pharmaceutical R&D teams and agrochemical manufacturers developing new therapeutic agents and crop protection solutions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, anti-infective agents, and other biologically active quinoline derivatives.
• Agrochemical Synthesis: Serves as a crucial building block for creating advanced fungicides, herbicides, and insecticides, leveraging the bioactivity of the quinoline scaffold.
• Material Science Research: Used in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-deficient quinoline core.
• Chemical Research & Development: Employed as a versatile synthon for constructing complex heterocyclic systems in medicinal and synthetic chemistry programs.
• Dye & Pigment Intermediate: Acts as a starting material for the synthesis of specialized quinoline-based dyes and functional colorants.

Basic Information

Product Name	Methyl 4-Chloro-6-Trifluoromethyl-Quinoline-2-Carboxylate
CAS No.	887267-67-6
Molecular Formula	C₁₂H₇ClF₃NO₂
Molecular Weight	289.64 g/mol
Synonyms	Methyl 4-chloro-6-(trifluoromethyl)quinoline-2-carboxylate; 4-Chloro-6-trifluoromethylquinoline-2-carboxylic acid methyl ester; 2-Quinolinecarboxylic acid, 4-chloro-6-(trifluoromethyl)-, methyl ester; Methyl 4-chloro-6-(trifluoromethyl)-2-quinolinecarboxylate; 887267-67-6; Methyl 4-chloro-6-trifluoromethylquinoline-2-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 4-Chloro-6-Trifluoromethyl-Quinoline-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural integrity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.