Description

6-Fluoro-2-Isopropylquinoline-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with significant synthetic utility. This compound is valued for its role as a key building block in the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of complex, fluorinated heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Synthesis: Serves as a building block for developing new generation fluorinated pesticides and herbicides, leveraging the stability imparted by the fluorine atom.
• Chemical Biology Probes: Employed in the design and synthesis of fluorescent tags or molecular probes for biochemical and cellular imaging applications.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic electronic materials due to its quinoline core.

Basic Information

Product Name	6-Fluoro-2-Isopropylquinoline-4-Carboxylic Acid
CAS No.	887206-68-0
Molecular Formula	C₁₃H₁₂FNO₂
Molecular Weight	233.24 g/mol
Synonyms	6-Fluoro-2-(1-methylethyl)-4-quinolinecarboxylic acid; 2-Isopropyl-6-fluoroquinoline-4-carboxylic acid; 4-Quinolinecarboxylic acid, 6-fluoro-2-(1-methylethyl)-; 6-Fluoro-2-propan-2-ylquinoline-4-carboxylic acid; FIQCA; 887206-68-0; 6-Fluoro-2-isopropyl-4-quinolinecarboxylic acid
EINECS	Contact for details

Quality Control

Our production of 6-Fluoro-2-Isopropylquinoline-4-Carboxylic Acid adheres to stringent quality management protocols. Every batch is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality systems are designed to support cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.