Description

1H-Indene-2-Carboxylic Acid, 1-Amino-2,3-Dihydro- is a specialized, high-value indene derivative that serves as a critical building block in advanced organic synthesis. Its unique fused-ring structure with both carboxylic acid and amino functional groups makes it a versatile intermediate for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and advanced materials sectors seeking to develop novel active ingredients or functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and plant growth regulators that require specific chiral or steric properties.
• Advanced Material Precursor: Employed in the creation of specialty polymers, dyes, and organic semiconductors where the indene core contributes to thermal stability and electronic properties.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Academic and R&D: A valuable tool for methodological studies in organic chemistry, including novel ring-forming reactions and functional group transformations.
• Fine Chemical Production: An intermediate in the multi-step synthesis of complex fragrance and flavor molecules.

Basic Information

Product Name	1H-Indene-2-Carboxylic Acid, 1-Amino-2,3-Dihydro-
CAS No.	887127-22-2
Molecular Formula	C10H11NO2
Molecular Weight	177.20 g/mol
Synonyms	1-Amino-2,3-dihydro-1H-indene-2-carboxylic acid; 2,3-Dihydro-1H-indene-2-carboxylic acid, 1-amino-; 1-Aminoindane-2-carboxylic acid; 1-Amino-2,3-dihydroindene-2-carboxylic acid; 2-Carboxy-1-aminoindane; 1-Amino-2-carboxyindane
EINECS	Contact for details

Quality Control

Our 1H-Indene-2-Carboxylic Acid, 1-Amino-2,3-Dihydro- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our standard quality commitment aligns with cGMP principles for advanced intermediates, and we can support custom synthesis to meet specific pharmacopeial or internal quality standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.