Description

1-Benzenesulfonyl-3-Iodo-1H-Pyrrolo[2,3-B]Pyridine is a high-purity, functionalized heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its unique molecular architecture, which combines a pyrrolopyridine core with benzenesulfonyl and iodine substituents, enabling precise cross-coupling and functionalization reactions. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and complex organic materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting kinase inhibition and other biological pathways.
• Organic Synthesis Building Block: Used in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to construct more elaborate molecular frameworks.
• Agrochemical Research: Serves as a scaffold for developing new active ingredients with potential herbicidal or insecticidal properties.
• Material Science: Investigated for the creation of organic electronic materials and functional dyes due to its conjugated system.
• Chemical Biology Probe Development: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.

Basic Information

Product Name	1-Benzenesulfonyl-3-Iodo-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	887115-53-9
Molecular Formula	C13H9IN2O2S
Molecular Weight	384.19 g/mol
Synonyms	3-Iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 3-iodo-1-[(phenylsulfonyl)]-; 1-(Benzenesulfonyl)-3-iodo-1H-pyrrolo[2,3-b]pyridine; 3-Iodo-1H-pyrrolo[2,3-b]pyridine 1-benzenesulfonate; 1-Benzenesulfonyl-3-iodo-7-azaindole; 3-Iodo-1-tosyl-1H-pyrrolo[2,3-b]pyridine (common name variant)
EINECS	Contact for details

Quality Control

Our 1-Benzenesulfonyl-3-Iodo-1H-Pyrrolo[2,3-B]Pyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.