Description

1-(4-Fluorophenyl)-5-Methyl-1,2,3-Triazole-4-Carboxylic Acid is a high-purity fluorinated triazole carboxylic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular architecture, which combines a fluorinated aromatic ring with a triazole-carboxylic acid functional group, enabling precise modifications to target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine-tuning the physicochemical properties of lead compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, especially in medicinal chemistry programs targeting enzymes and receptors where the fluorophenyl-triazole moiety can enhance binding affinity and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its structure can contribute to improved efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis, useful in asymmetric synthesis and material science.
• Material Science Research: Employed in the synthesis of functional polymers, metal-organic frameworks (MOFs), or organic electronic materials that require specific fluorinated heterocyclic components.
• Chemical Biology Probes: Utilized as a building block for creating fluorescent tags, photoaffinity labels, or other molecular probes to study biological processes.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	1-(4-Fluorophenyl)-5-Methyl-1,2,3-Triazole-4-Carboxylic Acid
CAS No.	887035-89-4
Molecular Formula	C10H8FN3O2
Molecular Weight	221.19 g/mol
Synonyms	4-Carboxy-1-(4-fluorophenyl)-5-methyl-1,2,3-triazole; 5-Methyl-1-(4-fluorophenyl)-1H-1,2,3-triazole-4-carboxylic acid; 1-(4-Fluorophenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylic acid; 1H-1,2,3-Triazole-4-carboxylic acid, 1-(4-fluorophenyl)-5-methyl-; 887035-89-4; 4-Fluorophenyl-5-methyl-triazole-4-carboxylic acid; FPMTCA
EINECS	Contact for details

Quality Control

Our production of 1-(4-Fluorophenyl)-5-Methyl-1,2,3-Triazole-4-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, NMR for structural confirmation, and Karl Fischer titration for moisture content. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications. We operate under a quality system designed to meet the expectations of cGMP and ISO standards for fine chemical manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Related Substances (HPLC)	Any individual impurity ≤0.5%; Total impurities ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.