Description

3-tert-Butoxycarbonylamino-3-(3-Fluoro-4-Methoxy-Phenyl)-Propionic Acid is a high-purity, non-natural amino acid derivative featuring a tert-butoxycarbonyl (Boc) protecting group and a fluorinated aromatic side chain. This compound is a critical building block in modern pharmaceutical research and development, enabling the synthesis of complex peptide-based therapeutics and small molecule drug candidates. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for the creation of novel active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of peptide-mimetic drugs and protease inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to introduce fluorinated, methoxy-substituted aromatic motifs into lead compounds.
• Peptide Synthesis: Serves as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis (SPPS).
• API Development: An advanced intermediate in the scalable production of candidate drugs targeting neurological and metabolic disorders.
• Chemical Biology Probes: Incorporation into fluorescent or affinity tags for studying protein-protein interactions and enzyme mechanisms.
• Process Chemistry: Used in route scouting and optimization for the commercial manufacturing of complex target molecules.

Basic Information

Product Name	3-tert-Butoxycarbonylamino-3-(3-Fluoro-4-Methoxy-Phenyl)-Propionic Acid
CAS No.	886506-21-4
Molecular Formula	C15H20FNO5
Molecular Weight	313.32 g/mol
Synonyms	Boc-3-(3-Fluoro-4-methoxyphenyl)-β-alanine; 3-[(tert-Butoxycarbonyl)amino]-3-(3-fluoro-4-methoxyphenyl)propanoic Acid; (R/S)-3-(Boc-amino)-3-(3-fluoro-4-methoxyphenyl)propionic Acid; 3-(N-Boc-amino)-3-(3-fluoro-4-methoxyphenyl)propanoic Acid; 886506-21-4; Boc-Fmp-OH; N-Boc-3-amino-3-(3-fluoro-4-methoxyphenyl)propionic acid
EINECS	Contact for details

Quality Control

Our production of 3-tert-Butoxycarbonylamino-3-(3-Fluoro-4-Methoxy-Phenyl)-Propionic Acid adheres to stringent quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements, supporting development under cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive (store away from light). For long-term storage, consider storage under inert atmosphere at lower temperatures (e.g., -20°C) to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.