Description

(3,6-Dimethyl-4-Oxo-3,4-Dihydro-Quinazolin-2-Ylsulfanyl)-Acetic Acid is a specialized quinazolinone derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique molecular scaffold, featuring a reactive acetic acid side chain, makes it a valuable building block for constructing complex heterocyclic compounds with targeted biological or material properties. This high-purity intermediate is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinazolinone-based drug candidates, particularly for applications in oncology and kinase inhibition research.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a monomer or functional additive in the creation of specialty polymers and advanced organic electronic materials.
• Chemical Biology: Employed as a molecular probe or linker in proteomics and bioconjugation studies due to its reactive thioether and carboxylic acid groups.
• Academic & Contract Research: Essential for synthetic methodology development and exploring new chemical spaces in university and CRO laboratories.

Basic Information

Product Name	(3,6-Dimethyl-4-Oxo-3,4-Dihydro-Quinazolin-2-Ylsulfanyl)-Acetic Acid
CAS No.	886500-82-9
Molecular Formula	C₁₂H₁₂N₂O₃S
Molecular Weight	264.30 g/mol
Synonyms	2-[(3,6-Dimethyl-4-oxo-3,4-dihydroquinazolin-2-yl)thio]acetic acid; (3,6-Dimethyl-4-oxo-3H-quinazolin-2-ylsulfanyl)acetic acid; Quinazolin-2-ylthioacetic acid derivative; 886500-82-9; 2-[(3,6-Dimethyl-4-oxoquinazolin-2(1H)-yl)thio]acetic acid
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity for this advanced intermediate. Production adheres to current Good Manufacturing Practices (cGMP) where applicable, and each lot is accompanied by a comprehensive Certificate of Analysis (COA). Our standard purity specification exceeds 97% (HPLC), with stringent controls on related substances and residual solvents to meet the exacting requirements of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.