Description

4-Bromo-2-Fluorobenzylmethylsulfone is a high-purity, synthetically valuable organosulfur compound characterized by its distinct halogenated benzyl structure. This chemical serves as a critical advanced pharmaceutical intermediate and versatile building block in modern organic synthesis. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides, leveraging its halogenated aromatic core.
• Ligand & Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the development of advanced polymers and liquid crystals with specific electronic or optical properties.
• Chemical Biology Probes: Utilized as a building block for synthesizing molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A fundamental substrate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	4-Bromo-2-Fluorobenzylmethylsulfone
CAS No.	886498-34-6
Molecular Formula	C8H8BrFO2S
Molecular Weight	267.11 g/mol
Synonyms	1-(Bromomethyl)-2-fluoro-4-(methylsulfonyl)benzene; (4-Bromo-2-fluorophenyl)(methylsulfonyl)methane; 4-Bromo-2-fluoro-α-(methylsulfonyl)toluene; 2-Fluoro-4-bromobenzyl methyl sulfone; Methyl (4-bromo-2-fluorobenzyl) sulfone; p-Bromo-o-fluorobenzylmethylsulfone
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluorobenzylmethylsulfone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.