Description

3-(3-Chloro-5-Fluorophenyl)Propanoic Acid is a high-purity aromatic carboxylic acid building block essential for advanced organic synthesis. This compound is valued for its unique halogenated phenylpropanoic acid structure, which serves as a critical intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, leveraging the bioactivity of the chloro-fluorophenyl moiety.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic electronic materials due to its stable aromatic core and functional carboxylic acid group.
• Chemical Research & Development: Employed in academic and industrial R&D for method development, catalysis studies, and exploring new reaction pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring specific halogenated phenylpropanoic acid derivatives.

Basic Information

Product Name	3-(3-Chloro-5-Fluorophenyl)Propanoic Acid
CAS No.	886498-21-1
Molecular Formula	C9H8ClFO2
Molecular Weight	202.61 g/mol
Synonyms	3-(3-Chloro-5-fluorophenyl)propanoic acid; 3-Chloro-5-fluorophenylpropionic Acid; 3-(3-Chloro-5-fluorophenyl)propionic Acid; 886498-21-1; 3-(3-Chloro-5-fluorophenyl)propanoate; β-(3-Chloro-5-fluorophenyl)propanoic acid; 3-(3-Chloro-5-fluorophenyl)propanoic acid (CAS 886498-21-1)
EINECS	Contact for details

Quality Control

Our 3-(3-Chloro-5-Fluorophenyl)Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be kept under an inert atmosphere (e.g., nitrogen) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.