Description

3-(3-Chloro-2-Fluorophenyl)Propionic Acid is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its core value lies in its unique molecular structure, which serves as a critical precursor for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate a specific halogenated phenylpropionic acid motif into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in therapeutic areas requiring fluorinated and chlorinated aromatic systems.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators where the 3-chloro-2-fluorophenyl moiety imparts specific biological activity.
• Liquid Crystal Material Precursor: Serves as a building block for fluorinated aromatic components in the manufacture of high-performance liquid crystal displays (LCDs).
• Organic Electronic Material Research: Employed in the development of novel organic semiconductors and charge-transport materials due to its electron-withdrawing halogen substituents.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific custom synthesis projects.
• Chemical Research & Development: Utilized in academic and industrial R&D labs for exploring new reactions and creating libraries of fluorinated compounds for screening.

Basic Information

Item	Detail
Product Name	3-(3-Chloro-2-Fluorophenyl)Propionic Acid
CAS No.	886498-12-0
Molecular Formula	C9H8ClFO2
Molecular Weight	202.61 g/mol
Synonyms	3-(3-Chloro-2-fluorophenyl)propanoic acid; 3-Chloro-2-fluorobenzene propionic acid; 3-(3-Chloro-2-fluorophenyl)propanoate; 2-Fluoro-3-chlorophenylpropionic acid; β-(3-Chloro-2-fluorophenyl)propionic acid; 886498-12-0; 3-(3-Chloro-2-fluoro-phenyl)-propionic acid
EINECS	Contact for details

Quality Control

Our 3-(3-Chloro-2-Fluorophenyl)Propionic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP (current Good Manufacturing Practice) compliance for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.