Description

2-(3-Fluoro-Phenyl)-Thiazole-4-Carboxylic Acid is a high-value fluorinated heterocyclic building block essential for advanced organic synthesis. This compound matters as a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique thiazole core and fluorine substituent impart desirable biological and physicochemical properties. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and anti-infective research.
• Agrochemical Synthesis: Used to develop advanced fungicides and herbicides, leveraging the bioactivity of the thiazole moiety.
• Material Science Research: Serves as a building block for creating specialty polymers and organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and cellular processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client projects.

Basic Information

Product Name	2-(3-Fluoro-Phenyl)-Thiazole-4-Carboxylic Acid
CAS No.	886369-06-8
Molecular Formula	C10H6FNO2S
Molecular Weight	223.22 g/mol
Synonyms	2-(3-Fluorophenyl)-1,3-thiazole-4-carboxylic acid; 2-(3-Fluorophenyl)-4-thiazolecarboxylic acid; 4-Thiazolecarboxylic acid, 2-(3-fluorophenyl)-; 886369-06-8; 2-(3-Fluoro-phenyl)-thiazole-4-carboxylic acid; 2-(m-Fluorophenyl)thiazole-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-(3-Fluoro-Phenyl)-Thiazole-4-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.