Description

2,2,2-Trifluoro-1-m-Tolyl-Ethylamine is a high-purity fluorinated aromatic amine building block of significant interest in advanced organic synthesis. Its core value lies in the unique combination of the electron-withdrawing trifluoromethyl group and the reactive amine functionality, enabling precise modifications to molecular scaffolds. This compound is primarily needed by R&D and production chemists in the pharmaceutical and agrochemical industries for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of monomers and functionalized polymers with tailored surface properties and chemical resistance.
• Fluorine Chemistry Building Block: Essential for introducing the trifluoroethylamine moiety into complex molecules to modulate their lipophilicity, metabolic stability, and binding affinity.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific projects requiring high-value fluorinated intermediates.

Basic Information

Product Name	2,2,2-Trifluoro-1-m-Tolyl-Ethylamine
CAS No.	886368-58-7
Molecular Formula	C9H10F3N
Molecular Weight	189.18 g/mol
Synonyms	α-(Trifluoromethyl)-m-tolylmethylamine; 1-(3-Methylphenyl)-2,2,2-trifluoroethanamine; m-Tolyl(trifluoromethyl)methylamine; 2,2,2-Trifluoro-1-(3-methylphenyl)ethanamine; 1-(3-Methylphenyl)-2,2,2-trifluoroethylamine; (3-Methylphenyl)(trifluoromethyl)methanamine; 886368-58-7; 2,2,2-Trifluoro-1-(m-tolyl)ethylamine
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-1-m-Tolyl-Ethylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability, consistency, and reliability for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture. Keep away from incompatible materials such as strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.