Description

2-n-Boc-2-Aminomethyl-3-(3-Methoxy-Phenyl)-Propionic Acid is a protected amino acid derivative, specifically a Boc-protected phenylalanine analog, serving as a critical chiral building block in organic synthesis. Its primary value lies in enabling the controlled synthesis of complex peptides and peptidomimetics, where the Boc group provides orthogonal protection for the amine functionality. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly in the development of active pharmaceutical ingredients (APIs) and novel therapeutic compounds.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of peptide-based drugs and complex active pharmaceutical ingredients (APIs).
• Peptidomimetic Research: Used in medicinal chemistry for designing and synthesizing non-peptide compounds that mimic peptide chains.
• Solid-Phase Peptide Synthesis (SPPS): A crucial protected amino acid derivative for the sequential assembly of peptides on resin.
• Chemical Biology Probes: Incorporation into molecular probes for studying protein-protein interactions and enzyme function.
• Combinatorial Chemistry: Serves as a versatile scaffold in libraries for high-throughput screening of bioactive molecules.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule development.

Basic Information

Product Name	2-n-Boc-2-Aminomethyl-3-(3-Methoxy-Phenyl)-Propionic Acid
CAS No.	886364-91-6
Molecular Formula	C17H25NO5
Molecular Weight	323.38 g/mol
Synonyms	Boc-3-(3-Methoxyphenyl)-D,L-alanine; (2-((tert-Butoxycarbonyl)amino)methyl)-3-(3-methoxyphenyl)propanoic Acid; 2-((tert-Butoxycarbonylamino)methyl)-3-(3-methoxyphenyl)propanoic Acid; 2-(Boc-aminomethyl)-3-(3-methoxyphenyl)propionic Acid; N-Boc-3-(3-Methoxyphenyl)-β-alanine; tert-Butyl [2-carboxy-2-(3-methoxyphenyl)ethyl]carbamate; Boc-3-(3-Methoxyphenyl)-β-homoalanine
EINECS	Contact for details

Quality Control

Our production of 2-n-Boc-2-Aminomethyl-3-(3-Methoxy-Phenyl)-Propionic Acid adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity suitable for research and cGMP manufacturing. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.