Description

4-Chloro-6,7-Difluoro-Quinoline-3-Carbonitrile is a high-value, multi-functional heterocyclic building block and advanced pharmaceutical intermediate. Its unique halogenated quinoline core structure makes it a critical precursor for synthesizing complex molecules with targeted biological activity. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in oncology, antiviral, and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Serves as a core structure for creating new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Used in the development of organic electronic materials, such as OLEDs and semiconductors, due to its electron-deficient quinoline system.
• Chemical Biology Probe: Employed as a scaffold for designing molecular probes and inhibitors to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	4-Chloro-6,7-Difluoro-Quinoline-3-Carbonitrile
CAS No.	886362-75-0
Molecular Formula	C10H3ClF2N2
Molecular Weight	224.59 g/mol
Synonyms	4-Chloro-6,7-difluoroquinoline-3-carbonitrile; 6,7-Difluoro-4-chloroquinoline-3-carbonitrile; 3-Cyano-4-chloro-6,7-difluoroquinoline; Quinoline-3-carbonitrile, 4-chloro-6,7-difluoro-; 886362-75-0; 4-Chloro-6,7-difluoro-3-quinolinecarbonitrile
EINECS	Contact for details

Quality Control

Our 4-Chloro-6,7-Difluoro-Quinoline-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.