Description

4-Chloro-6-Fluoro-Quinoline-3-Carbonitrile is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its versatile molecular scaffold, which serves as a critical precursor for constructing complex pharmacophores and functional materials. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of quinoline-based drug candidates, particularly in kinase inhibitor and antimicrobial research.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, leveraging the biological activity of the quinoline core.
• Material Science Research: Serves as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Biology Probes: Employed in the synthesis of fluorescent tags or molecular probes for studying biological processes.
• Academic & Contract Research: Essential for method development and exploratory chemistry in university and CRO (Contract Research Organization) laboratories.
• Fine Chemical Production: A versatile intermediate for the custom synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	4-Chloro-6-Fluoro-Quinoline-3-Carbonitrile
CAS No.	886362-73-8
Molecular Formula	C10H4ClFN2
Molecular Weight	206.60 g/mol
Synonyms	4-Chloro-6-fluoroquinoline-3-carbonitrile; 6-Fluoro-4-chloroquinoline-3-carbonitrile; 3-Cyano-4-chloro-6-fluoroquinoline; Quinoline-3-carbonitrile, 4-chloro-6-fluoro-; 886362-73-8; 4-Chloro-6-fluoro-3-quinolinecarbonitrile
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-Fluoro-Quinoline-3-Carbonitrile is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.