Description

6-Bromo-4-Chloro-8-Fluoro-Quinoline-3-Carbonitrile is a high-value, multi-halogenated quinoline derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its precise molecular architecture makes it indispensable for constructing complex heterocyclic frameworks with tailored electronic and steric properties. This compound is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly for kinase inhibitors, antiviral agents, and anti-cancer compounds.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and pesticides due to its halogenated quinoline core.
• Material Science: Serves as a precursor for organic semiconductors, liquid crystals, and photoactive materials.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce complex quinoline motifs into target molecules.
• Academic & Contract Research: Essential for methodological studies and library synthesis in medicinal and process chemistry.

Basic Information

Product Name	6-Bromo-4-Chloro-8-Fluoro-Quinoline-3-Carbonitrile
CAS No.	886362-71-6
Molecular Formula	C₁₀H₃BrClFN₂
Molecular Weight	285.50 g/mol
Synonyms	6-Bromo-4-chloro-8-fluoroquinoline-3-carbonitrile; 8-Fluoro-6-bromo-4-chloroquinoline-3-carbonitrile; 3-Cyano-6-bromo-4-chloro-8-fluoroquinoline; Quinoline-3-carbonitrile, 6-bromo-4-chloro-8-fluoro-; 886362-71-6
EINECS	Contact for details

Quality Control

Our 6-Bromo-4-Chloro-8-Fluoro-Quinoline-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.