Description

8-n-Boc-5,6,7,8-Tetrahydro-1,8-Naphthyridin-2-Methylamine is a high-purity, protected amine derivative used as a critical building block in advanced organic synthesis. This compound matters because it provides a versatile and reactive scaffold for constructing complex nitrogen-containing heterocycles, which are prevalent in active pharmaceutical ingredients. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its heterocyclic core structure.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating molecular probes to study enzyme function and biological pathways.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity advanced intermediates.
• Academic Research: Utilized in university and institutional labs for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	8-n-Boc-5,6,7,8-Tetrahydro-1,8-Naphthyridin-2-Methylamine
CAS No.	886362-43-2
Molecular Formula	C15H23N3O2
Molecular Weight	277.36 g/mol
Synonyms	tert-Butyl 2-(aminomethyl)-5,6,7,8-tetrahydro-1,8-naphthyridine-8(7H)-carboxylate; 2-(Aminomethyl)-5,6,7,8-tetrahydro-1,8-naphthyridine-8(7H)-carboxylic acid tert-butyl ester; 8-Boc-2-AMINOMETHYL-5,6,7,8-TETRAHYDRO-1,8-NAPHTHYRIDINE; 8-Boc-5,6,7,8-tetrahydro-1,8-naphthyridin-2-ylmethanamine; 8-(tert-Butoxycarbonyl)-5,6,7,8-tetrahydro-1,8-naphthyridin-2-methylamine; Boc-Protected THN Methylamine
EINECS	Contact for details

Quality Control

Our 8-n-Boc-5,6,7,8-Tetrahydro-1,8-Naphthyridin-2-Methylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring the material is suitable for use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.