Description

tert-Butyl 4-(5-Bromo-1H-Indol-3-Yl)-3,6-Dihydro-1(2H)-Pyridinecarboxylate is a high-value, advanced pharmaceutical intermediate featuring a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, serving as a versatile building block for the synthesis of novel therapeutic agents. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new drug candidates, particularly those targeting central nervous system and oncological pathways.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Library Synthesis: Valuable building block for creating diverse compound libraries for high-throughput screening.
• Chemical Biology Probes: Serves as a starting material for developing molecular probes to study biological pathways and protein functions.
• Process Chemistry Development: Employed in route scouting and scale-up studies for the commercial manufacturing of new chemical entities.

Basic Information

Product Name	tert-Butyl 4-(5-Bromo-1H-Indol-3-Yl)-3,6-Dihydro-1(2H)-Pyridinecarboxylate
CAS No.	886361-90-6
Molecular Formula	C18H21BrN2O2
Molecular Weight	377.28 g/mol
Synonyms	tert-Butyl 4-(5-bromo-1H-indol-3-yl)-3,6-dihydro-2H-pyridine-1-carboxylate; 1-Boc-4-(5-bromo-1H-indol-3-yl)-1,2,3,6-tetrahydropyridine; 4-(5-Bromo-1H-indol-3-yl)-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester; 5-Bromo-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole-1-carboxylic acid, 1,1-dimethylethyl ester; 886361-90-6; tert-Butyl 4-(5-bromoindol-3-yl)-3,6-dihydropyridine-1(2H)-carboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(5-Bromo-1H-Indol-3-Yl)-3,6-Dihydro-1(2H)-Pyridinecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to consistent quality and supply reliability supports your critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.