Description

(R)-Piperidine-3-Carboxylic Acid Hcl is a high-purity chiral building block and intermediate of significant importance in advanced organic synthesis. Its value lies in its enantiomeric purity, which is critical for developing compounds with specific biological activity. This product is essential for research and development laboratories and production facilities in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and production of novel drug candidates, especially in central nervous system (CNS) and metabolic disorder therapeutics.
• Asymmetric Synthesis: Used as a precursor or catalyst ligand in stereoselective chemical reactions to create enantiomerically pure compounds.
• Agrochemical Development: Serves as a building block for synthesizing advanced, chiral pesticides and herbicides with improved efficacy and environmental profiles.
• Peptidomimetics Research: Incorporated into the design of peptide analogs and conformationally restricted scaffolds for medicinal chemistry.
• Chemical Biology Probes: Utilized in the development of molecular probes to study enzyme function and biological pathways.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	(R)-Piperidine-3-Carboxylic Acid Hydrochloride
CAS No.	885949-15-5
Molecular Formula	C6H12ClNO2
Molecular Weight	165.62 g/mol
Synonyms	(R)-Nipecotic Acid Hydrochloride; (R)-3-Piperidinecarboxylic Acid Hydrochloride; (R)-3-Carboxypiperidine Hydrochloride; (R)-Homonipecotic Acid Hydrochloride; (3R)-Piperidine-3-carboxylic acid hydrochloride; (R)-BAY-×-1005; (R)-BAY × 1005; (R)-BAYx1005
EINECS	Contact for details

Quality Control

Our (R)-Piperidine-3-Carboxylic Acid Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high enantiomeric excess (ee) and chemical purity, meeting the stringent requirements for pharmaceutical R&D. Standard testing includes chiral HPLC, NMR, and residual solvent analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and assay is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.