Description

7-Chloro-3-Piperidin-4-Ylquinolin-2(1H)-One is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, serving as a key building block for novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in the synthesis of targeted therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of new chemical entities.
• Kinase Inhibitor Development: Serves as a privileged structure in the design and synthesis of potential kinase inhibitors for targeted cancer therapies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and drug discovery methodologies.

Basic Information

Product Name	7-Chloro-3-Piperidin-4-Ylquinolin-2(1H)-One
CAS No.	885654-36-4
Molecular Formula	C14H15ClN2O
Molecular Weight	262.74 g/mol
Synonyms	7-Chloro-3-(4-piperidinyl)-2(1H)-quinolinone; 3-(Piperidin-4-yl)-7-chloroquinolin-2(1H)-one; 7-Chloro-3-piperidin-4-yl-1H-quinolin-2-one; 2(1H)-Quinolinone, 7-chloro-3-(4-piperidinyl)-; 885654-36-4; 7-Chloro-3-(piperidin-4-yl)quinolin-2(1H)-one
EINECS	Contact for details

Quality Control

Our 7-Chloro-3-Piperidin-4-Ylquinolin-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.