Description

7-Fluoro-3-Piperidin-4-Ylquinolin-2(1H)-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique quinolinone-piperidine hybrid structure. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for synthesizing novel drug candidates. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new therapeutic agents, particularly in the areas of central nervous system (CNS) and oncology targets.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its versatile chemical scaffold.
• Protease Inhibitor Development: The quinolinone core is a privileged structure in the design of enzyme inhibitors, including kinase and protease inhibitors.
• CNS Drug Discovery: Employed in research for developing potential treatments for neurological and psychiatric disorders.
• Oncology Research: Serves as a building block for compounds being investigated for anti-cancer properties.
• Chemical Biology Probes: Used to create tool compounds for studying biological processes and target validation.

Basic Information

Product Name	7-Fluoro-3-Piperidin-4-Ylquinolin-2(1H)-One
CAS No.	885654-35-3
Molecular Formula	C14H15FN2O
Molecular Weight	246.28 g/mol
Synonyms	7-Fluoro-3-(4-piperidinyl)-2(1H)-quinolinone; 3-(Piperidin-4-yl)-7-fluoroquinolin-2(1H)-one; 7-Fluoro-3-piperidin-4-yl-1H-quinolin-2-one; 2(1H)-Quinolinone, 7-fluoro-3-(4-piperidinyl)-; 885654-35-3; 7-Fluoro-3-(piperidin-4-yl)quinolin-2(1H)-one
EINECS	Contact for details

Quality Control

Our 7-Fluoro-3-Piperidin-4-Ylquinolin-2(1H)-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical development partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Unknown Impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.