Description

6-Iodo-4-Methyl-3-Indazole Carboxylic Acid is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines an indazole scaffold with halogen and carboxylic acid functionalities, enabling precise structural modifications. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and complex molecular libraries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small-molecule drugs, particularly kinase inhibitors and other enzyme modulators.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive indazole core.
• Chemical Biology Probe Synthesis: Serves as a versatile scaffold for creating molecular probes to study biological pathways and protein functions.
• Material Science: Potential building block for advanced organic materials, such as ligands for metal-organic frameworks (MOFs) or specialty polymers.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create diverse compound libraries.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.

Basic Information

Product Name	6-Iodo-4-Methyl-3-Indazole Carboxylic Acid
CAS No.	885521-24-4
Molecular Formula	C9H7IN2O2
Molecular Weight	302.07 g/mol
Synonyms	4-Methyl-6-iodo-1H-indazole-3-carboxylic acid; 6-Iodo-4-methyl-1H-indazole-3-carboxylic acid; 1H-Indazole-3-carboxylic acid, 6-iodo-4-methyl-; 885521-24-4; 6-Iodo-4-methylindazole-3-carboxylic acid; 4-Methyl-6-iodoindazole-3-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 6-Iodo-4-Methyl-3-Indazole Carboxylic Acid is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with high-purity standards suitable for research and development applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles via validated methods such as HPLC, NMR, and mass spectrometry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.