Description

3,4-1H-Indazole-Dicarboxylic Acid is a high-purity, multifunctional heterocyclic building block of significant interest in advanced organic synthesis. Its dicarboxylic acid functionality and indazole core structure make it a versatile precursor for constructing complex molecular architectures. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly those targeting kinase inhibition or other biological pathways where the indazole scaffold is relevant.
• Organic Synthesis Building Block: Used in coupling reactions, amide bond formation, and as a precursor for generating complex heterocyclic compounds and functionalized ligands.
• Agrochemical Research: Serves as a core structure in the synthesis of novel herbicides, fungicides, or plant growth regulators requiring specific heterocyclic motifs.
• Material Science Precursor: Potential use in the synthesis of organic semiconductors, metal-organic frameworks (MOFs), or specialty polymers where dicarboxylic acid linkers are required.
• Bioconjugation & Probe Development: The carboxylic acid groups enable conjugation to biomolecules or solid supports for creating chemical probes and diagnostic tools.

Basic Information

Product Name	3,4-1H-Indazole-Dicarboxylic Acid
CAS No.	885519-87-9
Molecular Formula	C9H6N2O4
Molecular Weight	206.16 g/mol
Synonyms	1H-Indazole-3,4-dicarboxylic acid; 3,4-Indazoledicarboxylic Acid; 3,4-Pyrazole-4,5-dicarboxylic acid (fused); Indazole-3,4-dicarboxylic Acid; 1H-Indazole-3,4-dicarboxylic acid (9CI); 3,4-Dicarboxyindazole; 4,5-Dicarboxyindazole
EINECS	Contact for details

Quality Control

Our 3,4-1H-Indazole-Dicarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key specifications such as assay purity and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.