Description

5-Hydroxy-1H-Indazole-3-Carboxylic Acid is a high-purity heterocyclic carboxylic acid building block of significant interest in advanced organic synthesis. Its unique indazole core functionalized with both a phenolic hydroxyl and a carboxylic acid group makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Serves as a building block for creating new generations of herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs) due to its chelating potential.
• Material Science: Employed in the synthesis of organic semiconductors, dyes, and photostabilizers for advanced polymeric materials.
• Biochemical Tool Compound: Acts as a precursor or core structure for developing enzyme inhibitors and molecular probes in biochemical assays.

Basic Information

Product Name	5-Hydroxy-1H-Indazole-3-Carboxylic Acid
CAS No.	885518-94-5
Molecular Formula	C8H6N2O3
Molecular Weight	178.15 g/mol
Synonyms	5-Hydroxy-1H-indazole-3-carboxylic acid; 1H-Indazole-3-carboxylic acid, 5-hydroxy-; 5-Hydroxyindazole-3-carboxylic acid; 3-Carboxy-5-hydroxyindazole; 5-Hydroxy-1H-indazole-3-carboxylic acid (CAS 885518-94-5); 5-HO-1H-Indazole-3-COOH
EINECS	Contact for details

Quality Control

Our 5-Hydroxy-1H-Indazole-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.