Description

(S)-(Tetrahydro-2H-Pyran-2-Yl)Methanamine Hydrochloride is a high-purity chiral amine hydrochloride salt, serving as a critical building block in advanced organic synthesis. Its defined stereochemistry and salt form provide enhanced stability and handling properties for demanding chemical processes. This intermediate is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries developing active pharmaceutical ingredients (APIs) and other high-value chiral compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) targets.
• Asymmetric Synthesis: Used as a chiral auxiliary or resolving agent in catalytic asymmetric reactions to produce enantiomerically pure compounds.
• Ligand Precursor: Serves as a starting material for the synthesis of complex ligands used in metal-catalyzed transformations.
• Agrochemical Research: Employed in the development of chiral active ingredients for crop protection products.
• Academic & Process Chemistry: A valuable reagent for methodological studies in organic chemistry and for scaling up synthetic routes in process development.

Basic Information

Product Name	(S)-(Tetrahydro-2H-Pyran-2-Yl)Methanamine Hydrochloride
CAS No.	885331-14-6
Molecular Formula	C6H14ClNO
Molecular Weight	151.63 g/mol
Synonyms	(S)-2-(Aminomethyl)tetrahydro-2H-pyran hydrochloride; (S)-Tetrahydro-2H-pyran-2-ylmethanamine hydrochloride; (S)-THP-Methanamine HCl; (S)-Aminomethyltetrahydropyran hydrochloride; (S)-(2-Pyranylmethyl)amine hydrochloride; (S)-2-(Aminomethyl)tetrahydropyran hydrochloride; (S)-Tetrahydropyran-2-ylmethylamine hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-(Tetrahydro-2H-Pyran-2-Yl)Methanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and production. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent exposure to atmospheric moisture, which can affect stability and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.