Description

(4-Fluoro-3-Nitro-Benzyl)-Carbamic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. This compound matters for its role as a key precursor in the development of novel active pharmaceutical ingredients (APIs), particularly those targeting complex disease pathways. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex drug molecules, particularly in medicinal chemistry programs.
• Protease Inhibitor Research: Used in the development of inhibitors for various protease enzymes, which are targets for antiviral and anticancer therapies.
• Peptidomimetic Synthesis: Serves as a protected amino acid derivative for constructing peptide-like compounds with enhanced stability and bioavailability.
• Agrochemical Development: Employed in the research and synthesis of novel herbicides and pesticides, leveraging its fluorinated nitroaromatic structure.
• Material Science Research: Acts as a monomer or functionalization agent in the creation of specialized polymers and advanced materials.
• Chemical Biology Probes: Utilized to create labeled compounds or probes for studying biological mechanisms and enzyme functions.

Basic Information

Product Name	(4-Fluoro-3-Nitro-Benzyl)-Carbamic Acid tert-Butyl Ester
CAS No.	885280-67-1
Molecular Formula	C₁₂H₁₅FN₂O₄
Molecular Weight	270.26 g/mol
Synonyms	N-Boc-4-Fluoro-3-nitrobenzylamine; tert-Butyl N-[(4-Fluoro-3-nitrophenyl)methyl]carbamate; Boc-4-Fluoro-3-nitrobenzylamine; (4-Fluoro-3-nitrobenzyl)carbamic acid 1,1-dimethylethyl ester; 1,1-Dimethylethyl N-[(4-fluoro-3-nitrophenyl)methyl]carbamate; N-(tert-Butoxycarbonyl)-4-fluoro-3-nitrobenzylamine; Boc-NH-CH2-(4-F-3-NO2-Ph)
EINECS	Contact for details

Quality Control

Our (4-Fluoro-3-Nitro-Benzyl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere when not in use to prevent degradation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.