Description

3-Cyano-5-Iodo (1H)Indazole CAS NO 885278-27-3 is a high-purity, functionalized indazole derivative serving as a critical building block in advanced organic synthesis. This compound matters for its unique molecular architecture, combining a cyano group and an iodine atom on the indazole core, which provides versatile handles for further chemical modification. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a monomer or functional unit in the creation of specialty polymers and advanced organic materials.
• Chemical Biology: Employed as a probe or linker in bioconjugation and proteomics research due to its reactive iodine moiety.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig couplings.
• Academic & Contract Research: A valuable reagent for methodological studies and library synthesis in academic and CRO (Contract Research Organization) settings.

Basic Information

Product Name	3-Cyano-5-Iodo (1H)Indazole
CAS No.	885278-27-3
Molecular Formula	C8H4IN3
Molecular Weight	269.04 g/mol
Synonyms	5-Iodo-1H-indazole-3-carbonitrile; 1H-Indazole-3-carbonitrile, 5-iodo-; 5-Iodoindazole-3-carbonitrile; 885278-27-3; 3-Cyano-5-iodoindazole; 5-Iodo-3-cyanoindazole; 5-Iodo-1H-indazole-3-carbonitrile; AI3-28535
EINECS	Contact for details

Quality Control

Our 3-Cyano-5-Iodo (1H)Indazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and compliance with research-grade standards. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat and incompatible materials. This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.