Description

2-(4-Bromo-Phenyl)-4-Chloro-5-Methyl-Quinazoline is a high-purity, synthetically valuable halogenated quinazoline derivative. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis, enabling the development of novel active molecules. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for targeted R&D and production.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other biologically active quinazoline-based compounds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and other transformations to construct complex molecular architectures.
• Material Science Precursor: Investigated for the creation of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in optoelectronic devices.
• Chemical Biology Probe: Serves as a scaffold for developing molecular probes to study enzyme function and cellular pathways.

Basic Information

Product Name	2-(4-Bromo-Phenyl)-4-Chloro-5-Methyl-Quinazoline
CAS No.	885277-89-4
Molecular Formula	C15H10BrClN2
Molecular Weight	349.61 g/mol
Synonyms	4-Chloro-2-(4-bromophenyl)-5-methylquinazoline; 2-(4-Bromophenyl)-4-chloro-5-methylquinazoline; 5-Methyl-2-(4-bromophenyl)-4-chloroquinazoline; Quinazoline, 2-(4-bromophenyl)-4-chloro-5-methyl-; 885277-89-4; 2-(p-Bromophenyl)-4-chloro-5-methylquinazoline
EINECS	Contact for details

Quality Control

Our 2-(4-Bromo-Phenyl)-4-Chloro-5-Methyl-Quinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive and should be handled under inert atmosphere for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.