Description

4-Chloro-2-(4-Chloro-Phenyl)-7-Fluoro-Quinazoline is a high-purity, multi-halogenated quinazoline derivative, a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with specific biological or physical properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Used in the development of new herbicides and fungicides due to its bioactive quinazoline core.
• Material Science: Serves as a building block for organic electronic materials and liquid crystals.
• Chemical Synthesis: Employed in cross-coupling reactions and as a scaffold for constructing complex heterocyclic libraries.
• Biochemical Research: Utilized as a standard or probe in biochemical assays and mechanism-of-action studies.

Basic Information

Product Name	4-Chloro-2-(4-Chloro-Phenyl)-7-Fluoro-Quinazoline
CAS No.	885277-75-8
Molecular Formula	C14H7Cl2FN2
Molecular Weight	293.12 g/mol
Synonyms	4-Chloro-2-(4-chlorophenyl)-7-fluoroquinazoline; 2-(4-Chlorophenyl)-4-chloro-7-fluoroquinazoline; 7-Fluoro-2,4-bis(4-chlorophenyl)quinazoline (common misnomer); 4-Chloro-2-(4'-chlorophenyl)-7-fluoroquinazoline; Quinazoline, 4-chloro-2-(4-chlorophenyl)-7-fluoro-; 885277-75-8; FCQ Intermediate
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-(4-Chloro-Phenyl)-7-Fluoro-Quinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and traceability for critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from degradation. For long-term storage, consider an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.