Description

4-Chloro-2-(4-Chloro-Phenyl)-6-Methyl-Quinazoline is a high-purity, synthetically valuable quinazoline derivative. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis, enabling the development of novel active ingredients. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of complex molecules targeting various therapeutic and functional applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those with quinazoline-based scaffolds for oncology, CNS, and anti-inflammatory applications.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Acts as a building block for creating organic electronic materials, such as charge-transport layers or luminescent compounds.
• Chemical Synthesis: Serves as a versatile reagent for constructing complex heterocycles via cross-coupling, cyclization, and functional group transformation reactions.
• Biochemical Tool Compound: Utilized in academic and industrial research as a probe or inhibitor to study specific enzymatic pathways and biological mechanisms.

Basic Information

Product Name	4-Chloro-2-(4-Chloro-Phenyl)-6-Methyl-Quinazoline
CAS No.	885277-69-0
Molecular Formula	C15H10Cl2N2
Molecular Weight	289.16 g/mol
Synonyms	4-Chloro-2-(4-chlorophenyl)-6-methylquinazoline; 2-(4-Chlorophenyl)-4-chloro-6-methylquinazoline; 6-Methyl-2,4-bis(4-chlorophenyl)quinazoline (common misnomer, verify structure); Quinazoline, 4-chloro-2-(4-chlorophenyl)-6-methyl-; 4-Chloro-2-(p-chlorophenyl)-6-methylquinazoline; 2-(4-Chloro-phenyl)-4-chloro-6-methyl-quinazoline; 4,2'-Dichloro-6-methyl-2-phenylquinazoline
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-(4-Chloro-Phenyl)-6-Methyl-Quinazoline is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ISO standards for intermediate manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.