Description

2-(5-Trifluoromethyl-Pyridin-2-Yl)-Ethylamine is a high-value pyridine derivative featuring a reactive primary amine group and a stable trifluoromethyl substituent. This compound is a critical building block in modern pharmaceutical and agrochemical research, prized for its ability to impart metabolic stability and modulate physicochemical properties in target molecules. It is primarily sought by R&D chemists and process development scientists in the life sciences sector for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances bioactivity.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized to create molecular probes and fluorescent tags for studying biological pathways and protein interactions.

Basic Information

Product Name	2-(5-Trifluoromethyl-Pyridin-2-Yl)-Ethylamine
CAS No.	885277-36-1
Molecular Formula	C8H9F3N2
Molecular Weight	190.17 g/mol
Synonyms	2-(2-Aminoethyl)-5-(trifluoromethyl)pyridine; 5-(Trifluoromethyl)-2-pyridineethanamine; 2-(5-Trifluoromethyl-2-pyridinyl)ethylamine; 2-(5-Trifluoromethylpyridin-2-yl)ethan-1-amine; 2-Pyridineethanamine, 5-(trifluoromethyl)-; α-(5-Trifluoromethyl-2-pyridyl)ethylamine; 2-(5-Trifluoromethyl-2-pyridyl)ethylamine
EINECS	Contact for details

Quality Control

Our 2-(5-Trifluoromethyl-Pyridin-2-Yl)-Ethylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.