Description

4-Chloro-2-(4-Methoxy-Phenyl)-5-Methyl-Quinazoline is a high-purity, advanced pharmaceutical intermediate belonging to the quinazoline class of heterocyclic compounds. This compound is critical for the research and development of novel therapeutic agents, particularly in oncology and other disease areas. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Kinase Inhibitor Research: Serves as a core scaffold for the development of tyrosine kinase inhibitors and other targeted cancer therapies.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization processes.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Academic & Industrial R&D: Facilitates exploratory research in organic synthesis and new chemical entity (NCE) discovery.

Basic Information

Product Name	4-Chloro-2-(4-Methoxy-Phenyl)-5-Methyl-Quinazoline
CAS No.	885277-29-2
Molecular Formula	C₁₆H₁₃ClN₂O
Molecular Weight	284.74 g/mol
Synonyms	4-Chloro-2-(4-methoxyphenyl)-5-methylquinazoline; 2-(4-Methoxyphenyl)-4-chloro-5-methylquinazoline; 5-Methyl-4-chloro-2-(4-methoxyphenyl)quinazoline; Quinazoline, 4-chloro-2-(4-methoxyphenyl)-5-methyl-; CAS 885277-29-2
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-(4-Methoxy-Phenyl)-5-Methyl-Quinazoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements of pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.