Description

Quinazoline, 4-Chloro-6-Fluoro-2-Phenyl- is a high-purity, halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring a quinazoline core with strategic chloro and fluoro substituents, makes it a versatile and critical intermediate for the development of novel active compounds. This product is primarily targeted at pharmaceutical research and agrochemical development sectors, where it is used to construct molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small-molecule drug candidates, particularly in oncology and kinase inhibitor research.
• Agrochemical Research: Used to develop new active ingredients for crop protection products, leveraging its halogenated structure for bioactivity.
• Chemical Biology Probe Development: Serves as a scaffold for creating molecular tools to study biological pathways and protein functions.
• Material Science Research: Investigated as a building block for organic electronic materials and advanced functional polymers.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	Quinazoline, 4-Chloro-6-Fluoro-2-Phenyl-
CAS No.	885277-09-8
Molecular Formula	C₁₄H₈ClFN₂
Molecular Weight	258.68 g/mol
Synonyms	4-Chloro-6-fluoro-2-phenylquinazoline; 2-Phenyl-4-chloro-6-fluoroquinazoline; 4-Chloro-6-fluoro-2-phenyl-1,3-diazanaphthalene; Quinazoline, 4-chloro-6-fluoro-2-phenyl-; 885277-09-8; 4-Cl-6-F-2-Ph-quinazoline
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-Fluoro-2-Phenylquinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the consistency and reliability required for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, handling and packaging are performed under controlled lighting conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.