Description

3-Iodo-Imidazo[1,2-A]Pyridine-8-Carbaldehyde is a versatile and highly functionalized heterocyclic building block. This compound is of significant value in modern organic synthesis, particularly for constructing complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially for kinase inhibitors and other biologically active small molecules.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products.
• Material Science: Serves as a building block for creating advanced organic electronic materials and ligands for catalysis.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for biological target validation.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Library Synthesis: Utilized in parallel and combinatorial chemistry for generating diverse compound libraries for high-throughput screening.

Basic Information

Item	Details
Product Name	3-Iodo-Imidazo[1,2-A]Pyridine-8-Carbaldehyde
CAS No.	885276-00-6
Molecular Formula	C8H5IN2O
Molecular Weight	272.04 g/mol
Synonyms	8-Formyl-3-iodoimidazo[1,2-a]pyridine; 3-Iodoimidazo[1,2-a]pyridine-8-carboxaldehyde; Imidazo[1,2-a]pyridine-8-carbaldehyde, 3-iodo-; 885276-00-6; 3-Iodo-8-formylimidazo[1,2-a]pyridine
EINECS	Contact for details

Quality Control

Our 3-Iodo-Imidazo[1,2-A]Pyridine-8-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This material is light-sensitive and easily oxidized; allow the sealed container to reach room temperature before opening to minimize moisture ingress and degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.